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Nanocatalytic one-pot, four-component synthesis of some new triheterocyclic compounds consisting of pyrazole, pyran, and pyrimidinone rings†
Sadegh Dastkhoon,Zaiba Tavakoli,Saeed Khodabakhshi,Mojtaba Baghernejad,Masoud Khaleghi Abbasabadi
New Journal of Chemistry Pub Date : 07/22/2015 00:00:00 , DOI:10.1039/C5NJ01046B
Abstract

A new series of triheterocyclic compounds containing pyrazole, pyran, and pyrimidinone rings was synthesized via a one-pot condensation of ethylacetoacetate, hydrazine hydrate, barbituric acid, and aromatic aldehydes in the presence of catalytic amounts of titanium dioxide nanowires. Various functional groups were well tolerated under the optimized reaction conditions.

Graphical abstract: Nanocatalytic one-pot, four-component synthesis of some new triheterocyclic compounds consisting of pyrazole, pyran, and pyrimidinone rings
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