Two new sulfur heterocycle systems containing a 1,2-dithiole group, have been synthesized and characterized by IR, 1H NMR and single crystal X-ray crystallography. Optimum conditions for these closed-ring reactions have been studied and the possible reaction mechanism has been explored. A simple, fast, inexpensive and clean green synthesis route has been described here. The anti-cancer activity of these compounds was evaluated in terms of cell growth inhibition against human liver cancer cells HepG2.
![Graphical abstract: Novel ((3Z,5Z)-3,5-bis(phenylimino)-1,2-dithiolan-4-yl) and 3H-[1,2]dithiolo[3,4-b]quinolin-4(9H)-one heterocycles: an effective and facile green route](http://hg.y866.cn/compound/lib/scimg/usr/1/B808949C.jpg)
