Room-temperature nickel-catalysed cross-couplings of aryl chlorides with arylzincs†
Ning Liu,Li Wang,Zhong-Xia Wang
Chemical Communications Pub Date : 11/26/2010 00:00:00 , DOI:10.1039/C0CC03064C
Abstract

P,N,O-chelate nickel complexes efficiently catalyse the cross-coupling reaction of aryl chlorides with arylzinc reagents in a 1 ∶ 1 THF–NMP mixture. The reactions proceed at room temperature with low catalyst loading.

Graphical abstract: Room-temperature nickel-catalysed cross-couplings of aryl chlorides with arylzincs