960化工网
An indolocarbazole dimer as a new stereodynamic probe for chiral 1,2-diamines†
Hae-Geun Jeon,Min Jun Kim,Kyu-Sung Jeong
Organic & Biomolecular Chemistry Pub Date : 06/19/2014 00:00:00 , DOI:10.1039/C4OB00872C
Abstract

An indolocarbazole dimer that contains aldehyde groups at both ends was prepared by connecting two monomeric units through a rod-like 1,4-butadiynyl spacer. Upon mixing with chiral 1,2-diamines at room temperature, the dimer was in situ converted to the corresponding cyclic diimines in the presence of tetrabutylammonium acetate as a template. The resulting diimines fold to helical conformations of right-handed (P) or left-handed (M) orientations, depending on the absolute stereochemistries of chiral 1,2-diamines. The patterns and intensities of the CD spectra can be used to determine the absolute configurations and enantiomeric excesses of chiral 1,2-diamines.

Graphical abstract: An indolocarbazole dimer as a new stereodynamic probe for chiral 1,2-diamines
平台客服
平台客服
平台在线客服