960化工网
Self-propelled manganese oxide-based catalytic micromotors for drug delivery†
Linlin Wang,Jun Chen,Xiaomiao Feng,Wenjin Zeng,Ruiqing Liu,Xiujing Lin,Yanwen Ma,Lianhui Wang
RSC Advances Pub Date : 07/04/2016 00:00:00 , DOI:10.1039/C6RA13739C
Abstract

A manganese oxide-based catalytic tubular micromotor (PEDOT/MnO2) is described that displays effective autonomous motion in hydrogen peroxide with high speed (318.80 µm s−1) and can operate in very low levels of fuel, down to 0.4%. The polymer bilayer micromotor also exhibits efficient locomotion in different biological media including bovine serum albumin and bovine serum. Moreover, the micromotor is applied to deliver a chemotherapeutic anticancer drug, camptothecin, using electrostatic interactions, offering considerable potential for diverse clinical and biomedical applications such as drug delivery for theranostic microsystems.

Graphical abstract: Self-propelled manganese oxide-based catalytic micromotors for drug delivery
平台客服
平台客服
平台在线客服