Supramolecular nanofibers of self-assembling peptides and DDP to inhibit cancer cell growth†
Xiaoli Zhang,Can Li,Youzhi Wang,Caiwen Ou,Shenglu Ji,Minsheng Chen,Zhimou Yang
RSC Advances Pub Date : 06/08/2016 00:00:00 , DOI:10.1039/C6RA08357A
Abstract

We report in this paper a molecular hydrogel formed by adding cis-dichlorodiamineplatinum(II) (DDP) to a self-assembling taxol-peptide amphiphile. Our study provides a novel self-assembling nanomedicine and hydrogel to deliver two anti-cancer drugs simultaneously.

Graphical abstract: Supramolecular nanofibers of self-assembling peptides and DDP to inhibit cancer cell growth