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Surface group mediates the adsorption of in situ generated thrombin and its interaction with anti-thrombin in the protein corona of SBA-15†
Yunlong Li,Xiaofeng Liao,Pu Liu,Xiaoqiang Shang,Guicen Ma,Hao Chen,Jie Fan
RSC Advances Pub Date : 04/29/2014 00:00:00 , DOI:10.1039/C4RA02106A
Abstract

The surface groups of mesoporous silica (MPS) play an important role in mediating the hard protein corona (HPC) formation on its surface, leading to bio-identities with completely different procoagulant activities.

Graphical abstract: Surface group mediates the adsorption of in situ generated thrombin and its interaction with anti-thrombin in the protein corona of SBA-15
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