Synergic antimony–niobium pentoxide nanomeshes are fabricated on a large scale via the controllable decomposition of SbNbO₄ nanosheets, which are obtained from ultrathin hydrated niobium oxide (Nb₂O₅·nH₂O) layers. Synergizing the merits of highly active Sb and structurally stable Nb₂O₅, the nanomeshes exhibit enhanced charge-transfer kinetics, thus leading to a high capacity and good high-rate performance for sodium storage.