Herein, we report the radiosynthesis of ¹⁸F-difluoromethylarenes via the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and cyclotron-produced non-carrier added [¹⁸F]fluoride. The two key steps are a copper-catalysed cross-coupling reaction, and a Mn-mediated ¹⁸F-fluorodecarboxylation.