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tert-Butyl hydroperoxide (TBHP)-mediated oxidative self-coupling of amines to imines over a α-MnO2 catalyst†
Feng Wang,Min Wang,Shutao Xu,Jie Xu
Green Chemistry Pub Date : 01/07/2014 00:00:00 , DOI:10.1039/C3GC42312C
Abstract

We here demonstrate a simple, efficient and eco-friendly protocol for the direct synthesis of imines from amines via a facile α-MnO2 catalyzed-procedure at rt. Up to 13 benzylic, heterocyclic, and normal aliphatic imines were synthesized with 95–99% selectivity at 82–99% conversion.

Graphical abstract: tert-Butyl hydroperoxide (TBHP)-mediated oxidative self-coupling of amines to imines over a α-MnO2 catalyst
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