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Advances in loop-mediated isothermal amplification: integrated with several point-of-care diagnostic methods
Pin Gong,Taotao Zhang,Fuxin Chen,Lan Wang,Sai Jin,Xiaohuan Bai
Analytical Methods Pub Date : 06/26/2014 00:00:00 , DOI:10.1039/C4AY00330F
Abstract

Recent outbreaks linked to pathogenic bacteria heighten the need to develop rapid, sensitive, portable and low-cost pathogen diagnostic systems. Loop-mediated isothermal amplification (LAMP) is a powerful and novel gene amplification method emerging as a simple rapid diagnostic tool for early detection and identification of microbial disease. Herein, we highlight the recent advances concerning LAMP which is integrated with several innovative detection technologies, thus, this article also reviews the extensive application of these basic techniques in food-borne bacterial detection.

Graphical abstract: Advances in loop-mediated isothermal amplification: integrated with several point-of-care diagnostic methods
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