Analysis of the cercosporin polyketide synthase CTB1 reveals a new fungal thioesterase function†
Adam G. Newman,Anna L. Vagstad,Katherine Belecki,Jonathan R. Scheerer,Craig A. Townsend
Chemical Communications Pub Date : 10/29/2012 00:00:00 , DOI:10.1039/C2CC36010A
Abstract
The polyketide synthase CTB1 is demonstrated to catalyze pyrone formation thereby expanding the known biosynthetic repertoire of thioesterase domains in iterative, non-reducing polyketide synthases.