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An improved procedure for the preparation of 8-substituted guanines†
Ming Xu,Fabio De Giacomo,Duncan E. Paterson,Tesmol G. George,Andrea Vasella
Chemical Communications Pub Date : 05/20/2003 00:00:00 , DOI:10.1039/B302529B
Abstract

The preparation of 8-substituted guanines using a new phosphorus(III)-mediated cyclisation of 4-acylamino-5-nitrosopyrimidines as the key step is described.

Graphical abstract: An improved procedure for the preparation of 8-substituted guanines
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