The rapid reactivity of hydrofluoric acid (HF) and irregular Si-O network has been successfully applied in the chemical processing of glass/glass-ceramics surface. It is found that the low glass and diopside (D-G) interface binding energy will promote the reaction of HF and the residual glass phase at the interface, resulting in the formation of defects and the fall of grain. Raman spectroscopy has found that residual stress will be generated on the surface of the sample during corrosion, which will improve the performance of glass-ceramics, and the Vickers hardness increases from 761.5HV to 834.8HV. The corrosion process can be divided into three stages, including reaction of glass phase with hydrofluoric acid, formation of sediment on the surface of glass-ceramics and a corrosive layer. The whole process is closely related to insoluble crystal phase, which provides a theoretical basis for the study of hydrofluoric acid processing glass/glass-ceramics.