Artificial liner peptides that bind to the c face of hydroxyapatite (HA) were obtained by using the mRNA display method. The specific attachment to the c face was characterized with the adsorption isotherm of the peptides. The crystal growth of HA was found to be modulated by the particular peptides. The results of this study suggest that the amino acid sequence including Ala-Asn-Thr (ANT) is essential for the binding specificity.