By doping Ni into m-CoSeO₃, the structure of the catalyst was modified to improve the Ethanol Oxidation Reaction (EOR) catalytic performance. The catalyst exhibited excellent EOR catalytic activity (j₁₀ = 1.35 V) and high stability. Therefore, this catalyst is used in an innovative zinc–ethanol–air battery, which is more efficient and stable than the traditional zinc–air battery.