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Visible-light-induced reactions of methylenecyclopropanes (MCPs)
Hao-Zhao Wei,Yin Wei
Chemical Communications Pub Date : 02/01/2023 00:00:00 , DOI:10.1039/D2CC06957A
Abstract

Diverse, visible-light-induced transformations of methylenecyclopropanes (MCPs) have been reported in recent years, attracting significant attention from synthetic chemists. As readily accessible strained molecules, MCPs have sufficient reactivity to selectively generate different target products, through reactions with various radical species upon visible-light irradiation under regulated reaction conditions. These transformations can be classified into three subcategories of reaction pathway, forming ring-opened products, cyclopropane derivatives, and alkynes. These products include pharmaceutical intermediates and polycyclic/heterocyclic compounds that are challenging to obtain using traditional methods. This review summarizes the recent advancements in this field.

Graphical abstract: Visible-light-induced reactions of methylenecyclopropanes (MCPs)
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