Catalytic hydrodeoxygenation of neat levulinic acid into 2-methyltetrahydrofuran using a cobalt phosphine complex and Sc(OTf)3 co-catalytic system†,10.1039/D2GC04912K

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Catalytic hydrodeoxygenation of neat levulinic acid into 2-methyltetrahydrofuran using a cobalt phosphine complex and Sc(OTf)3 co-catalytic system†

Lijin Gan,Jin Deng

Green Chemistry Pub Date : 05/12/2023 00:00:00 , DOI:10.1039/D2GC04912K

Abstract

2-Methyltetrahydrofuran (2-MeTHF) is a biomass-based green solvent that has important applications in organic chemistry. Under solvent-free conditions, we investigated the efficient conversion of biomass platform molecules levulinic acid (LA) and γ-valerolactone (GVL) into 2-MeTHF. ≥97.0% yields of 2-MeTHF were achieved under relatively mild conditions (150 °C and 5 MPa H₂ for 24 h). The study of the reaction pathway showed that the role of Sc(OTf)₃ is to activate GVL as well as to promote the etherification reaction. In addition, studies of the transformation of carbohydrate-derived crude LA into 2-MeTHF demonstrated that the catalytic system is well tolerant to water and other impurities.