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Chemical constitutes and anti-obesity potential of seedlings of purple-leafed rice in high-fat diet induced obese mice†
Zenan Yang,Xiaofang Li,Dianwei Li,Cheng Wang,Yuanqi Song,Jingnan Ren,Kaikai Li,Hao Chen
Food & Function Pub Date : 11/10/2022 00:00:00 , DOI:10.1039/D2FO02374A
Abstract

The seedlings of purple leafed rice (SPLR) are characterized by high contents of anthocyanins and various polyphenols, whose total anthocyanin content can reach 15.16 mg g−1, indicating that SPLR may have many bioactivities. Therefore, in order to evaluate the anti-obesity potential value of SPLR, the nutrient components were first identified, and the anti-obesity effect of SPLR was evaluated with a high-fat diet (HFD) induced obese mouse model for 12 weeks. The results demonstrated that SPLR supplementation could alleviate HFD-induced obesity and suppress pro-inflammatory cytokine production and macrophage infiltration in epididymal white adipose tissue of HFD-induced obese mice. The findings indicated that supplementation with SPLR may contribute to preventing obesity and related complications.

Graphical abstract: Chemical constitutes and anti-obesity potential of seedlings of purple-leafed rice in high-fat diet induced obese mice
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