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Thermoneutral synthesis of spiro-1,4-cyclohexadienes by visible-light-driven dearomatization of benzylmalonates†
Quan-Qing Zhao,Julia Rehbein,Oliver Reiser
Green Chemistry Pub Date : 02/07/2022 00:00:00 , DOI:10.1039/D1GC04686A
Abstract

A visible-light-driven dearomatization of unactivated arenes with perfect atom economy to access spiro-1,4-cyclohexadienes is disclosed. Calculations suggest that the overall process is approximately thermoneutral, showcasing the special opportunities of light-driven processes to develop sustainable transformations that defy thermodynamic requirements.

Graphical abstract: Thermoneutral synthesis of spiro-1,4-cyclohexadienes by visible-light-driven dearomatization of benzylmalonates
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