960化工网
Implantable neural electrodes: from preparation optimization to application
Beilin Zhang,Ruijie Xie,Jiamin Jiang,Shiping Hao,Bin Fang,Jiaxin Zhang,Hua Bai,Bo Peng,Zhiyuan Liu,Li Fu
Journal of Materials Chemistry C Pub Date : 05/11/2023 00:00:00 , DOI:10.1039/D2TC05162A
Abstract

Implantable neural electrodes are important tools for interfacing with the neural system for recording and stimulation. The structural and mechanical mismatch between traditional rigid electrodes and nerve tissue can lead to an inflammatory response and signal degradation during long-term implantation. In recent years, researchers have continued to improve and innovate the material, structure, and implantation methods of electrodes to prepare flexible neural electrodes with better neural compatibility. In this review, the research progress on implantable neural electrodes is summarized from five aspects, namely materials, structures, stretchability, multifunctionality of flexible electrodes, and the application of implantable neural electrodes in nerve interfaces. Finally, the prospects for the implantable neural electrodes are discussed.

Graphical abstract: Implantable neural electrodes: from preparation optimization to application
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