NHC-mediated photocatalytic deoxygenation of alcohols for the synthesis of internal alkynes via a Csp3–Csp coupling reaction†,10.1039/D3OB01066J

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

NHC-mediated photocatalytic deoxygenation of alcohols for the synthesis of internal alkynes via a Csp3–Csp coupling reaction†

Xueji Ma,Liujie Wang,Xiaoqing Meng,Wenbo Li,Qin Wang,Yuke Gu,Lingna Qiu

Organic & Biomolecular Chemistry Pub Date : 07/31/2023 00:00:00 , DOI:10.1039/D3OB01066J

Abstract

NHC-mediated deoxygenation of alcohols under photocatalytic conditions is described. The process provides various alkyl radicals, which can react with 1-bromoalkyne via Csp³–Csp coupling to afford internal alkynes in moderate to good yields. The method offers a new and convenient approach to synthesize internal alkynes.