960化工网
Triazole-enabled, iron-catalysed linear/branched selective C–H alkylations with alkenes†
Silvia Cattani,Andrea Secchi,Lutz Ackermann,Gianpiero Cera
Organic & Biomolecular Chemistry Pub Date : 01/06/2023 00:00:00 , DOI:10.1039/D2OB02206K
Abstract

Iron-catalysed C–H alkylations with alkenes were achieved on benzamides by N-triazole assistance. A notable switch of the regioselectivity from linear to branched was observed depending on the nature of the olefin employed. The approach allowed for the synthesis of a family of decorated benzamides with ample scope and high levels of chemo-, regio- and site-selectivity.

Graphical abstract: Triazole-enabled, iron-catalysed linear/branched selective C–H alkylations with alkenes
平台客服
平台客服
平台在线客服