An unusual Me3SiI-promoted [4+2] annulation and reduction: an efficient approach to construct 4H-benzopyrans†
Feijun Wang,Mingliang Qu,Feng Chen,Li Li
Chemical Communications Pub Date : 11/15/2011 00:00:00 , DOI:10.1039/C1CC16028A
Abstract
Me3SiI-promoted reaction of salicylic aldehydes with β-dicarbonyl compounds provided a facile way to construct 4H-benzopyrans in moderate to good yields. This tandem reaction proceeds with high efficiency through nucleophilic addition, silyl enol ether formation, substitution, reduction, and intramolecular nucleophilic cyclization.
![Graphical abstract: An unusual Me3SiI-promoted [4+2] annulation and reduction: an efficient approach to construct 4H-benzopyrans](http://hg.y866.cn/compound/lib/scimg/usr/1/C1CC16028A.jpg)
