Visible light-induced N-radical 5-exo/6-endo cyclization of alkenyl amides: facile access to isoindolinones/isoquinolinones†,10.1039/D2OB00317A

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Visible light-induced N-radical 5-exo/6-endo cyclization of alkenyl amides: facile access to isoindolinones/isoquinolinones†

Zhen-Yao Lei,Kui Hu,Yuan-Xiang He,Shu Geng,Li-Na Chen,Shuai Zou,Li Pan,Zhi-Jun Ding,Feng Huang

Organic & Biomolecular Chemistry Pub Date : 03/03/2022 00:00:00 , DOI:10.1039/D2OB00317A

Abstract

An efficient N-centered radical intramolecular cyclization reaction of alkenyl amides induced by visible light was described. In this process, an alkenyl amide underwent 5-exo/6-endo cyclization to selectively yield two critical alkaloid structures, namely isoindolinones and isoquinolinones.