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Visible light mediated regioselective 1,3-oxylallylation of aryl cyclopropanes under redox-neutral conditions†
Ding-Xing Wang,Hui Wang,Yao Xu,Chi Zhang,Chao Feng
Organic Chemistry Frontiers Pub Date : 04/01/2023 00:00:00 , DOI:10.1039/D3QO00281K
Abstract

A photoredox catalysed 1,3-oxylallylation of aryl cyclopropanes was accomplished by reaction with carboxylic acids and allyl sulfones. The redox-neutral reaction proceeded in a highly regioselective manner under mild conditions with good functional group compatibility. Simple operation and successful application to the late-stage functionalization of several natural product and pharmaceutical molecule related carboxylic acids add extra merits to the current protocol.

Graphical abstract: Visible light mediated regioselective 1,3-oxylallylation of aryl cyclopropanes under redox-neutral conditions
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