The direct introduction of diverse fluorinated motifs into feedstock molecules and advanced intermediates is widely studied in pharmaceutical research and drug development. Among the emerging motifs, difluoromethyl CF₂H is isosteric and isopolar to hydroxy and thiol, while acting as a lipophilic hydrogen donor. These properties have prompted the recent remarkable progress made in direct difluoromethylation. In this context, photoredox catalysis serving difluoromethylation is a powerful strategy for the construction of CF₂H-containing organic compounds. This review describes the recent developments in visible-light-mediated radical difluoromethylation by means of easily accessible sources of CF₂H radical donors, with an emphasis on mechanistic considerations.