Rh(iii)-Catalyzed C–C coupling of unactivated C(sp3)–H bonds with iodonium ylides for accessing all-carbon quaternary centers†,10.1039/D2QO00667G

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Rh(iii)-Catalyzed C–C coupling of unactivated C(sp3)–H bonds with iodonium ylides for accessing all-carbon quaternary centers†

Pengfei Xie,Huixing Gao,Xingwei Li,Yuqin Jiang,Bingxian Liu

Organic Chemistry Frontiers Pub Date : 06/07/2022 00:00:00 , DOI:10.1039/D2QO00667G

Abstract

Rhodium-catalyzed inert C(sp³)–H activation/carbene insertion, which enables the construction of all-carbon quaternary centers, has been realized. Iodonium ylides are used as C1 synthons for efficient C–C bond formation with PhI being the only by-product. A rhodacycle has been synthesized and proved to be the active intermediate.