Application of an ephedrine chiral linker in a solid-phase, ‘asymmetric catch-release’ approach to γ-butyrolactones
Nessan J. Kerrigan,Panee C. Hutchison,Tom D. Heightman,David J. Procter
Chemical Communications Pub Date : 05/13/2003 00:00:00 , DOI:10.1039/B302471G
Abstract
A Sm(II)-mediated, asymmetric, intermolecular ketyl-olefin addition employing α,β-unsaturated esters linked to resin through an ephedrine ‘chiral link’ has been applied in a direct ‘asymmetric catch-release’ approach to γ-butyrolactones.
