Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles†,10.1039/D2RA06306A

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles†

Eleonora Colombo,Davide Andrea Coppini,Simone Maculan,Pierfausto Seneci,Benedetta Santini,Filippo Testa,Lucia Salvioni,Giovanni Maria Vanacore,Miriam Colombo,Daniele Passarella

RSC Advances Pub Date : 12/12/2022 00:00:00 , DOI:10.1039/D2RA06306A

Abstract

Hetero-nanoparticles self-assembled from a conjugate bearing folic acid as the targeting agent, and another bearing paclitaxel as the active agent are reported. Hetero-nanoparticles containing varying percentages of folic acid conjugates are characterised, and their biological activity is determined.