Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells†
David G. Smith,Ga-lai Law,Benjamin S. Murray,Robert Pal,David Parker
Chemical Communications Pub Date : 06/02/2011 00:00:00 , DOI:10.1039/C1CC11853F
Abstract
Image and spectral intensity from bicarbonate-selective europium(III) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO2, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide.
