Lanthanide(III) bis(perfluoroalkanesulfonyl)amide-catalysed reactions such as esterification and Baeyer–Villiger reactions in organic-fluorous biphase were performed to yield products with high TONs using the continuous-flow system of the small- and bench-scale apparatus which consisted of a reactor with a mechanical stirrer and a decanter. In the novel continuous-flow system, the Lewis acid catalyst is immobilised in a fluorous solvent while the substrates and the products obtained are dissolved in the mobile organic phase.