Aziridinyl anions from a chiral, nonracemic 2-isopropylidineaziridine: surprisingly diastereoselective alkylation reactions
J. F. Hayes,N. Prévost,I. Prokeš,M. Shipman,A. M. Z. Slawin,H. Twin
Abstract
Lithiation and alkylation of a 2-isopropylidineaziridine bearing an (S)-α-methylbenzyl group on nitrogen proceeds with high levels of diastereocontrol (80–90% de).
