A cascade C–H functionalization/cyclization reaction of N-arylpyridin-2-amines with α,β-unsaturated aldehydes for the synthesis of dihydroquinolinone derivatives under rhodium catalysis†,10.1039/C7OB00743D

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

A cascade C–H functionalization/cyclization reaction of N-arylpyridin-2-amines with α,β-unsaturated aldehydes for the synthesis of dihydroquinolinone derivatives under rhodium catalysis†

Zi-Jun Wu,Kenneth L. Huang,Zhi-Zhen Huang

Organic & Biomolecular Chemistry Pub Date : 05/31/2017 00:00:00 , DOI:10.1039/C7OB00743D

Abstract

A novel cascade C–H functionalization/cyclization reaction of N-arylpyridin-2-amines with α,β-unsaturated aldehydes has been developed under rhodium catalysis, affording dihydroquinolinone derivatives in moderate to excellent yields. A plausible mechanism of dual catalytic cycles by rhodium(III) catalysis is also proposed.