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A New Synthesis of 2-(2-Hydroxyalkyl)- and 2-(2-Aminoalkyl)-morpholines via 3-Morpholinones
Journal of Chemical Research, Synopses Pub Date : , DOI:10.1039/A808423H
Abstract

A new pathway for the synthesis of 2-(1-hydroxyalkyl)- and 2-(1-arylaminoalkyl)-morpholines via reaction of α-hydroxy- or α-amino-alkylation of 3-morpholinones followed by reduction with LiAlH4 of the intermediate compounds into the target substituted morpholines is proposed.

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