Highly loaded and ultrafine Pd nanoparticles were supported on graphene oxide (PdNPs-GO) via an in situ, simple and clean strategy on the basis of the direct redox reaction between Pd(OAc)2 and GO. A highly sensitive biosensor was developed for the detection of glucose based on the electrode modified with PdNPs-electrochemically reduced GO (PdNPs-ERGO). The glucose biosensor shows a wide linear range, low detection limit, good reproducibility and acceptable stability, providing a biocompatible platform for biosensing and biocatalysis.
