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PEDOT:TOS with PEG: a biofunctional surface with improved electronic characteristics†
Leslie H. Jimison,Adel Hama,Xenofon Strakosas,Vanessa Armel,Dion Khodagholy,Esma Ismailova,George G. Malliaras,Bjorn Winther-Jensen,Róisín M. Owens
Journal of Materials Chemistry Pub Date : 05/21/2012 00:00:00 , DOI:10.1039/C2JM32188B
Abstract

Devices based on conducting polymers offer great promise for interfacing with cells. Here, we use vapour phase polymerisation to create a biofunctional composite material of the conducting polymer poly(3,4-ethylenedioxythiophene):tosylate (PEDOT:TOS) and the biologically relevant poly(ethylene glycol) (PEG). On the addition of PEG, electroactivity of the PEDOT is maintained, conductivity is increased, and its performance as the active material in a transistor is unaffected. Both direct and indirect biocompatibility tests prove that PEDOT:TOS and PEDOT:TOS:PEG are biocompatible and nontoxic to mammalian cells. A functionalised PEG (PEG(COOH)) was additionally introduced into PEDOT:TOS to showcase the potential of this material for use in applications requiring biofunctionalisation.

Graphical abstract: PEDOT:TOS with PEG: a biofunctional surface with improved electronic characteristics
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