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Synthesis of 5-(but-3-en-1-ynyl)-2,2′-bithienyl and related compounds by Grignard coupling
Journal of the Chemical Society C: Organic Pub Date : , DOI:10.1039/J39660000089
Abstract

Acetylenic thiophens, ArC⋮CR (Ar = 2,2′-bithienyl-5-yl or 2-thienyl), have been prepared by a metal-catalysed Grignard coupling reaction, either from ArMgl and BrC⋮CR or from Arl and BrMgC⋮CR; the second method gave the better results. Some side-reactions are discussed.

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