960化工网
Formation of Grignard reagents from 3-bromo-NN-dimethylbenzylamine and 4-bromo-NN-diethylbenzylamine and their reactions with benzaldehyde
Journal of the Chemical Society C: Organic Pub Date : , DOI:10.1039/J39660000313
Abstract

3-Bromo-NN-dimethylbenzylamine and 4-bromo-NN-diethylbenzylamine failed to react with magnesium in ether in accordance with reports in the literature for similar compounds, but the Grignard reagents were easily obtained using tetrahydrofuran as the solvent. Reaction with benzaldehyde produced the expected alcohols; and, unexpectedly, the corresponding ketones were also obtained. By appropriate modification of the experimental procedure, either alcohol or ketone could be obtained exclusively.

平台客服
平台客服
平台在线客服