4-Alkyl-thio- and -dithio-azetidinones from penicillins
Journal of the Chemical Society D: Chemical Communications Pub Date : , DOI:10.1039/C29710001137
Abstract
Thiols react smoothly with penicillin sulphoxides to form 4-alkylthioazetidinones which, by treatment with phosphites or reaction with nucleophiles and alkyl iodides, afford 4-alkylthioazetidinones; some related reactions are also reported.
