Aptamer biosensor for label-free impedance spectroscopy detection of proteins based on recognition-induced switching of the surface charge†
Marcela C. Rodriguez,Abdel-Nasser Kawde,Joseph Wang
Chemical Communications Pub Date : 07/12/2005 00:00:00 , DOI:10.1039/B506571B
Abstract
The recognition of proteins by aptamer-modified electrode transducers reverses the surface charge and leads to a novel label-free impedance spectroscopy bioelectronic detection protocol based on a decrease in the electron transfer resistance.
