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Chemical synthesis and biological study of 4β-carboxymethyl-epiafzelechin acid, an osteoprotective compound from the rhizomes of Drynaria fortunei†
MedChemComm Pub Date : 05/25/2012 00:00:00 , DOI:10.1039/C2MD20082A
Abstract

The chemically synthesized active osteoprotective component 12 of Drynaria fortunei (kunze) J. Sm showed potent proliferative activity on UMR-106 osteoblast-like cells and selectively activate ERE-dependent gene transcription mediated by ERα but not ERβ.

Graphical abstract: Chemical synthesis and biological study of 4β-carboxymethyl-epiafzelechin acid, an osteoprotective compound from the rhizomes of Drynaria fortunei
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