Role of the leaving group in the base-catalysed hydrolysis of pseudo-esters
Journal of the Chemical Society D: Chemical Communications Pub Date : , DOI:10.1039/C2971000822A
Abstract
The relative insensitivity of the rate of hydrolysis of γ-pseudo-esters to the leaving group compared to that of the normal esters emphasises that the conjugative ability is an important factor in determining the rate of hydrolysis of esters.