Asymmetric autocatalysis induced by meteoritic amino acids with hydrogen isotope chirality†‡
Masako Shimizu,Daisuke Nishiyama,Masateru Ito,Hitomi Ozawa
Chemical Communications Pub Date : 06/24/2009 00:00:00 , DOI:10.1039/B908754K
Abstract

Achiral meteoritic amino acids, glycine and α-methylalanine, with hydrogen isotope (D/H) chirality, acted as the source of chirality in asymmetric autocatalysis with amplification of ee to afford highly enantioenriched 5-pyrimidyl alkanols.

Graphical abstract: Asymmetric autocatalysis induced by meteoritic amino acids with hydrogen isotope chirality