Blue fluorescent deoxycytidine analogues: convergent synthesis, solid-state and electronic structure, and solvatochromism†
David W. Dodd,Kalen N. Swanick,Jacquelyn T. Price,Allison L. Brazeau,M. J. Ferguson,Nathan D. Jones,Robert H. E. Hudson
Organic & Biomolecular Chemistry Pub Date : 12/10/2009 00:00:00 , DOI:
10.1039/B919921GAbstract
We report the synthesis and photospectroscopic characterisation of intrinsically fluorescent triazole-appended cytidines. Fluorescence was found to be highly dependent on solvent conditions. X-Ray crystallographic data show the proton of the exocyclic amine of the nucleobase and the triazole N3 engaged in a H-bond.
