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Biosynthesis of aminoglycoside antibiotics: cloning, expression and characterisation of an aminotransferase involved in the pathway to 2-deoxystreptamine†
Fanglu Huang,Yanyan Li,Jinquan Yu,Jonathan B. Spencer
Chemical Communications Pub Date : 11/05/2002 00:00:00 , DOI:10.1039/B209799K
Abstract

The gene btrR from Bacillus circulans has been cloned and expressed and shown to produce a protein which catalyses the transamination of 2-deoxy-scyllo-inosose to give 2-deoxy-scyllo-inosamine, an intermediate in the biosynthesis of 2-deoxystreptamine.

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