Carbonylative coupling of N-chloroamines with alcohols: synthesis of esterification reagents†
Zhiping Yin,Zechao Wang,Xiao-Feng Wu
Organic & Biomolecular Chemistry Pub Date : 03/26/2018 00:00:00 , DOI:10.1039/C8OB00462E
Abstract

Herein we report a new method for the carbonylative synthesis of carbamates. Starting from N-chloroamines and alcohols, with copper or Pd/C as the catalyst, the corresponding carbamates were produced in moderate to good yields. No additional oxidant or base is needed in this system. Notably, the produced benzotriazole-carboxylates can be used as esterification reagents.

Graphical abstract: Carbonylative coupling of N-chloroamines with alcohols: synthesis of esterification reagents