Casuarine-6-O-α-d-glucoside and its analogues are tight binding inhibitors of insect and bacterial trehalases†,10.1039/B926600C

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Casuarine-6-O-α-d-glucoside and its analogues are tight binding inhibitors of insect and bacterial trehalases†

Francesca Cardona,Andrea Goti,Camilla Parmeggiani,Paolo Parenti,Matilde Forcella,Paola Fusi,Laura Cipolla,Shirley M. Roberts,Gideon J. Davies,Tracey M. Gloster

Chemical Communications Pub Date : 02/23/2010 00:00:00 , DOI:10.1039/B926600C

Abstract

Two novel casuarine-6-α-D-glucoside analogues, as well as the parent compound, were synthesized and tested as inhibitors towards Chironomus riparius, mammalian pig kidney and Escherichia coli trehalases. Their potent and selective activity is promising for the development of new insecticides.