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Catalytic coupling of nitriles with amines to selectively form imines under mild hydrogen pressure†
Dipankar Srimani,Moran Feller,Yehoshoa Ben-David,David Milstein
Chemical Communications Pub Date : 11/02/2012 00:00:00 , DOI:10.1039/C2CC36639H
Abstract

Imines are selectively formed by coupling of nitriles and amines under mild hydrogen pressure. The reaction is catalyzed by a bipyridine-based PNN Ru(II) pincer complex and proceeds under mild, neutral conditions at 4 bar of H2.

Graphical abstract: Catalytic coupling of nitriles with amines to selectively form imines under mild hydrogen pressure
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