Carbon nanotubes activate inflammatory signalling through binding to Siglec-14
MichelleKGreene,ChristopherJScott
Abstract
Discovery of a novel axis through which multi-walled carbon nanotubes (MWCNTs) elicit toxicity in human macrophages, involving the propagation of inflammatory signalling via the Siglec-14-DAP12-Syk pathway, and how it may be controlled pharmacologically.
